The global aptamers market size is expected to reach USD 10.88 billion by 2030, according to a new report by Grand View Research Inc. The market is expected to expand at a CAGR of 24.54% from 2023 to 2030. The growth of the market is attributed to the strong presence of product pipelines and their expected launch during the forecast period. Some of the products in the pipeline are E10030 (Fovista), ARC1905 (Zimura) by IVERIC Bio, Inc., AGRO100 by Antisoma Research Ltd, NOX-A12 (olaptesed pegol) & NOX-E36 (emapticap pegol) by NOXXON Pharma, and NU172 by ARCA Biopharma, Inc. AGRO100 completed the phase 1 clinical trial for multiple oncology indications such as non-small cell lung cancer, solid tumors, and renal cancer.
In addition, initiatives undertaken by regulatory agencies such as the U.S. FDA, Health Canada, EMA, COFEPRIS, MHRA, and CDSCO to support the research and development in the field of aptamers are projected to fuel market growth. For instance, in March 2020, IVERIC Bio, Inc. received Fast Track designation from the U.S. FDA for Zimura for the treatment of patients with GA secondary to age-related macular degeneration (AMD). Zimura is a chemically synthesized pegylated RNA aptamer, administered by intravitreal injection. It acts by inhibiting complement factor C5 which is responsible for the development of AMD.
Companies are studying aptamers for applications such as western blotting, ELISA, therapeutics, and flow cytometry. Custom aptamer selection is considered to be an important service offered by existing aptamer players to life sciences companies. Thrombin aptamers, cocaine aptamers, and theophylline aptamers are some of the most frequently used customized aptamers for research and development activities. Thus, the surge in numbers of biotech and pharma companies working on research related to aptamers and related technologies has opened up new avenues for the growth of this market.
Gather more insights about the market drivers, restrains and growth of the Aptamers Market
Detailed Segmentation:
Type Insights
Based on type, aptamers market is segmented into nucleic acid aptamers and peptide aptamers. Nucleic acid segment held the highest market share of 78.19% in 2022 and is expected to witness the highest growth during the forecast period. At present, many companies are investigating the mechanism of action of nucleic acid aptamers for the treatment of various disorders including age related muscular degeneration (AMD). For instance, in June 2021, the U.S. Food and Drug Administration (FDA) granted written agreement under Special Protocol Assessment (SPA) to IVERIC BIO (formerly known as Ophthotech Corporation) for the design of GATHER2 phase 3 clinical trial of Zimura for treatment of patients with GA secondary to AMD. This approval is expected to boost the segment growth.
Application Insights
Based on application, the aptamers market is segmented into diagnostics, therapeutics development, research and development, and others. The research & development segment held the highest market share of 31.38% in 2022. The growth of segment is attributed to rising demand for aptamers coupled with increasing research activities in this field have paved the way for aptamers demand in research and development field. There are various strategic initiatives undertaken by key players like collaborations, partnerships, & agreements for R&D of novel aptamers based diagnostic and therapeutic products. For instance, in June 2021, SomaLogic and Ixaka Ltd entered into a research collaboration with an aim to support the discovery and development of aptamers based bispecific therapeutics. This collaboration evaluates the safety and efficacy of antigen specific SOMAmer reagents. Such an initiative is expected to boost the segment growth.
Regional Insights
North America region dominated the aptamers market with a share of 44.48% in 2022. The rising prevalence of chronic diseases, strong healthcare infrastructure, and growing interest of research laboratories in aptamer field are some of the major factors for the dominance of the region. Furthermore, in April 2022, Noxxon Pharma announced that it will present top line result data for its NOX-A12 GLORIA trial in brain cancer at the 2022 American Society of Clinical Oncology annual meeting.
Browse through Grand View Research's Biotechnology Industry Research Reports.
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Key Companies & Market Share Insights
Major players are adopting strategies such as modification in the existing product, approval of new products, and mergers & acquisitions for product enhancements and regional expansion to attain a greater market share. For instance, in January 2023, Aptamer Group collaborated with BaseCure Therapeutics for the development of Optimer-targeted therapies. Such initiatives can open new avenues of growth for applications of aptamers in therapeutics.
Some of the prominent players in the global aptamers market include:
• SomaLogic
• Aptamer Group
• Aptadel Therapeutics
• Base Pair Biotechnologies
• Noxxon Pharma
• Vivonics Inc.
• Aptagen, LLC
• TriLink Biotechnologies
• Altermune LLC
• AM Biotechnologies
Aptamers Market Segmentation
Grand View Research has segmented the global aptamers market on the basis of type, application, and region:
Aptamers Type Outlook (Revenue, USD Million; 2018 - 2030)
• Nucleic Acid Aptamer
• Peptide Aptamer
Aptamers Application Outlook (Revenue, USD Million; 2018 - 2030)
• Diagnostics
• Therapeutics
• Research & Development
• Others
Aptamers Regional Outlook (Revenue, USD Million; 2018 - 2030)
• North America
o U.S.
o Canada
• Europe
o Germany
o UK
o France
o Italy
o Spain
o Denmark
o Sweden
o Norway
• Asia Pacific
o Japan
o China
o India
o Australia
o Thailand
o South Korea
• Latin America
o Brazil
o Mexico
o Argentina
• MEA
o South Africa
o Saudi Arabia
o UAE
o Kuwait
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