Dydrogesterone is a synthetic progestogen that is used as a hormonal contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, and premenstrual syndrome. It can also be used to induce labor in pregnant women who are at least 34 weeks pregnant. Dydrogesterone is available as an oral tablet and vaginal tablet.
The most common side effects of dydrogesterone include headache, breast tenderness, nausea, bloating, and changes in weight or appetite. Rare but serious side effects include blood clots in the lungs or legs.
Dydrogesterone is generally well tolerated and effective when used as prescribed. It may be a good choice for women who cannot take estrogen-containing contraceptives due to health concerns.
It is used to help transgender people transition from male to female by suppressing testosterone levels. Dydrogesterone comes in pill form and must be taken every day. It can take up to six months for the full effects of the medication to be seen. Some common side effects of dydrogesterone include breast enlargement, mood swings, and changes in sex drive.