Sickle cell anemia is an inherited blood disorder where red blood cells become rigid and crescent-shaped due to a genetic change, blocking blood flow and reducing oxygen delivery throughout the body. Symptoms in children often start around infancy and include fatigue from anaemia, pain episodes, swelling of hands and feet, frequent infections and delayed growth. Early recognition and care are essential — consult Dr Nandini Hazarika for proper diagnosis and guidance to manage symptoms and improve quality of life.